Core framework: Every longevity company faces integration risk—the risk that its offering remains isolated from primary care and community mental health, limiting reach and sustainability.

Five design principles to reduce integration risk:

Indication selection. Choose disease indications that primary-care clinicians recognize and manage. Avoid speculative 'aging' as sole indication.
Mental-health integration. Build expectations management, psychosocial support, and adherence coaching into the product from day one.
Biomarker actionability. Ensure biomarkers or diagnostics feed into clinical decision-making, not just curiosity.
Primary-care workflow design. Design for how primary-care clinicians actually work (time-poor, multitasking), not ideal scenarios.
Equity from design. Diverse population representation in validation, cost models that work in low-income settings, and explicit measurement of equity outcomes.

Deck 5: Playbooks & Integration